RIG-I: a multifunctional protein beyond a pattern recognition receptor
نویسندگان
چکیده
منابع مشابه
Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5
Most organisms rely on innate immune receptors to recognize conserved molecular structures from invading microbes. Two essential innate immune receptors, RIG-I and MDA5, detect viral double-stranded RNA in the cytoplasm. The inflammatory response triggered by these RIG-I-like receptors (RLRs) is one of the first and most important lines of defense against infection. RIG-I recognizes short RNA l...
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ژورنال
عنوان ژورنال: Protein & Cell
سال: 2017
ISSN: 1674-800X,1674-8018
DOI: 10.1007/s13238-017-0431-5